ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue
Dataset: Single-unit electrophysiological responses of human cortical organoids to varying electrical stimulation parameters<p dir="ltr">This dataset contains single-neuron spiking activity from human induced pluripotent stem cell (iPSC)-derived cortical organoids subjected to targeted electrical stimulation. The data was collected using a high-density multielectrode array (MEA) system (BioCAM DupleX, 3Brain).</p>
HKU DataHub + figshare + Loughborough Research Repository + UP Research Data Repository2026 · Astronomical catalogue
Raw movie of a typical single-molecule TIRF experiment. These data fully demonstrate stochastic transitions of the V-ATPase between active and inactive modes and their regulation by specific inhibitor Bafilomycin A1.<h4 dir="ltr">This video shows single-molecule acidification kinetics of native vacuolar-type ATPase (V-ATPase) in individual synaptic vesicles (SVs) purified from rat brain, labeled with the pH-sensitive lipid pHrodo-DOPE and imaged by total internal reflection fluorescence (TIRF) microscopy (Olympus TIRF system, 532 nm excitation, iXon 897 EMCCD camera, 500 ms exposure per frame, 3 s cycle time)
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig 1 C, D and Fig S1 C Dataset<p dir="ltr">Corresponding data to Figure 1 C, D and S1 Figure C - mixed vs uniform fiber diameter sheath length and log sheath length dataset</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig S2 I, J Dataset<p dir="ltr">Dataset associated with Figure S2 I, J - qPCR analysis of Piezo1 mRNA expression in isolated mouse oligodendrocyte lineage cells</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig 2 F Dataset<p dir="ltr">Dataset underlying Figure 2F - calcium imaging of rat oligodendrocytes treated with DMSO (control) or Yoda1</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig 4 G Dataset<p dir="ltr">Dataset underlying Figure 4 G - % of myelinated sheaths with outfoldings (myelin membrane misdirected away from the axon) at postnatal days 15 and 30 in Piezo1 CKO versus Control (flox/flox) ventral spinal cord white matter.</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig S3 B C D Dataset<p dir="ltr">Dataset underlying Fig S3 B-D, RNAScope analysis of Piezo1 mRNA expression in different spinal cord cell types</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig S2 M Datasets<p dir="ltr">Datasets corresponding to Figure S2 M - % of BCAS1 or CNPase+ cells that express Piezo1-tdTomato</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig 2 B, C and S2 A, B, E, F Dataset<p dir="ltr">Datasets of myelin sheath lengths and corresponding fiber diameters</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig 4 C D E and S4 K L Datasets<p dir="ltr">Datasets underlying Figures 4 C-E and S4 K, L - myelin sheath thickness at postnatal days 15 and 30 in the ventral spinal cord white matter of Piezo1 cKO versus Control mice</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig S4 E-J Datasets<p dir="ltr">Dataset underlying Figure S4 E-J - calculated g-ratios for postnatal days 15 and 30 in the ventral spinal cord white matter of Piezo1 cKO versus Control mice</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig 3 E, F and S3 H-L Dataset<p dir="ltr">Dataset underlying Figure 3 E, F as well as S3 H-L - spinal cord myelin sheath lengths and corresponding axon diameters from Piezo1 CKO vs Controls (fl/fl or CNP wt/Cre)</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig 4 B and S4 A C D Dataset<p dir="ltr">Dataset underlying Figures 4B and S4 A, C, D - % myelinated axons and diameters of myelinated (vs unmyelinated) axons at postnatal day 5, 15, 30 in ventral spinal cord white matter of Piezo1 cKO versus Control mice.</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig 3 H and S3 M Dataset<p dir="ltr">Dataset underlying Figure 3H and S3M - % and density of oligodendrocyte lineage cells in the ventral and lateral spinal cord white matter at postnatal day 15</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig S1 A, B Dataset<p dir="ltr">Dataset associated with S1 A, B - diameters of myelinated microfibers</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig 3 A Dataset<p dir="ltr">Dataset underlying Fig 3 A - qPCR of Piezo1 conditional knockout mouse oligodendrocytes</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig S2 C, D, G, H Dataset<p dir="ltr">Dataset for Figure S2 C, D, G, H - % MBP positive cells and % OLs ensheathing fibers for curvature sensing candidate knockdown </p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig S3 E F Dataset<p dir="ltr">Dataset underlying Figure S3 E, F - number of myelin sheaths formed by oligodendrocytes in the mouse cortex of Piezo1 cKO vs Control (floxed) mice</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue
Fig 3 C and S3 G Dataset<p dir="ltr">Dataset underlying Figure 3C and S3 G - myelin sheath lengths in the mouse cortex of Piezo1 cKO vs Control mice</p>
figshare + Loughborough Research Repository2026 · Astronomical catalogue · restricted
Supporting Data for "Neuroprotective effects of bavachin in ischemic stroke models"<p dir="ltr">This dataset provides supporting in vivo and in vitro experimental data for a research project on the neuroprotective effects of bavachin in ischemic stroke models. About the in vivo data, the dataset includes evidence demonstrating the successful establishment of a middle cerebral artery occlusion (MCAO) model in adult rats, as well as measurements of cerebral infarct volume and neur
figshare + Loughborough Research Repository2026 · Astronomical catalogue · unknown
Data supporting Compans, Mastrolia et al., 'In vivo modulation of network activity drives the nanoscale reorganisation of axo-axonic synapses at the axon initial segment'. Nature Communications, 2026.<p dir="ltr">See Readme file for details. All files have been scanned for viruses before uploading.</p>
figshare2026 · Astronomical catalogue
Nozawa x10MAP-STED raw data and statistics used for main Figures 1-5 and Extended Data Figures 1-10.<p dir="ltr">This study investigates the molecular organization of glutamate receptors within hippocampal excitatory synapses. Using approximately tenfold tissue expansion combined with STED microscopy, we mapped endogenous AMPA receptors, NMDA receptors and PSD-95 at near-receptor-complex scale. The data show that mesoscale receptor nanodomains can arise without discrete multi-receptor clustering
ZivaHub2023 · dataset · unknown
Investigating the mechanism of action underlying the ability of kappa opioid receptor agonists to promote oligodendrocyte differentiation and myelination in vitro<p><strong>Multiple sclerosis (MS) is a demyelinating, autoimmune, neuroinflammatory disease that affects ~3 million people worldwide. In MS, the body’s immune system attacks the protective myelin coating surrounding nerve cells, impairing salutatory conduction. Unfortunately, there is no cure for MS, and due to the scarcity of effective treatment options that promote recovery, researchers look to