figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue
Figure 2 M6BUP free base aqueous nanosuspension production and characterization<p dir="ltr">M6BUP, a prodrug of buprenorphine was manufactured as aqueous nanosuspension and physiochemical properties characterized. </p>
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Astronomical catalogue
Figure 1 M6BUP free base synthesis and characterization<p dir="ltr">Schematic illustration of <a href="" target="_blank">M6BUP prodrug </a>promoiety synthesis and characterization</p>
ZivaHub2026 · dataset
Karlah Mansauda: Overcoming the PEGylation Dilemma in Lipid Nanoparticles for CD47 Silencing: Enhanced Macrophage-Mediated Tumour Clearance<p dir="ltr">Background: Silencing CD47, a “don’t eat me” signal on breast cancer cells, with small interfering RNA (siRNA), restores macrophage-mediated phagocytosis. Lipid nanoparticles (LNPs) deliver siRNA, but the stabilising PEG layer tends to trap them in endosomes (pH <6) (the PEGylation dilemma). We aim to develop acid-cleavable PEG-lipid LNP (PEGCL-LNP/siCD47) that will ‘shed’ in acidic e
ZivaHub2026 · dataset
Shriya Phadnis: Designing and optimising oxygen-loaded microbubbles for anticancer applications<p dir="ltr">Background: Tumour hypoxia remains a major obstacle to effective cancer treatment, contributing to therapeutic resistance and poor clinical outcomes. Localised tumour reoxygenation has the potential to improve the efficacy of conventional therapies; however, no clinically established oxygen delivery strategy currently exists. Oxygen-loaded microbubbles offer a promising platform for t
figshare2026 · Astronomical catalogue
Supporting data and materials for the systematic review and meta-analysis of extracellular vesicles as nanocarriers for therapeutic agent delivery in ischemic stroke<p dir="ltr">This repository contains the supporting data and materials for the systematic review and meta-analysis entitled: "Extracellular Vesicles as Nanocarriers for Therapeutic Agent Delivery in Ischemic Stroke: A Systematic Review and Meta-Analysis of Animal Studies".</p><p dir="ltr">The repository includes the extracted quantitative data used for meta-analyses and the risk-of-bias assessmen