{
"version": "1.0",
"query": {
"text": null,
"operator": "and",
"filters": [
{
"field": "concept",
"op": "descendant_of",
"value": "local:modality:single-cell-rna-seq",
"evidence": null
}
],
"evidence_policy": "standard"
},
"sort": null,
"page": {
"size": 25
}
}figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Data Sheet 1_Exploiting RAG1-deficient chickens to construct a single-cell transcriptional atlas of chicken heterophils during inflammation.xlsxIntroduction<p>Avian heterophils naturally lack myeloperoxidase (MPO), making chicken a unique evolutionary model for investigating MPO-independent innate immune strategies. However, the molecular programs governing heterophil maturation and activation remain largely unexplored.</p>Methods<p>Using single-cell RNA sequencing in a RAG1-deficient chicken model, we mapped heterophil maturation during
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Supplementary file 1_Case Report: Melanocyte-associated mTORC1-related molecular features in an atypical large congenital melanocytic naevus.docx<p>Congenital melanocytic naevi (CMN) are usually associated with activating alterations in NRAS or BRAF, but some extensive lesions lack detectable canonical hotspot variants. We report a 9-year-old boy with a large craniofacial CMN involving the face, scalp, upper eyelid and bulbar conjunctiva, with deep extension, mechanical ptosis and secondary amblyopia. Histology showed benign dermal melanoc
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 2_Longitudinal single-cell analysis identifies a chemotherapy-suppressed proliferative program associated with adverse prognosis in neuroblastoma.xlsxBackground<p>High-risk neuroblastoma frequently relapses after intensive therapy, but the treatment-associated malignant-neuroblast programs that inform baseline tumor risk remain incompletely defined. We used longitudinal single-cell/single-nucleus RNA-seq data to identify post-treatment transcriptional changes in malignant neuroblasts and evaluated their prognostic relevance in diagnostic bulk R
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 1_Exploiting RAG1-deficient chickens to construct a single-cell transcriptional atlas of chicken heterophils during inflammation.docxIntroduction<p>Avian heterophils naturally lack myeloperoxidase (MPO), making chicken a unique evolutionary model for investigating MPO-independent innate immune strategies. However, the molecular programs governing heterophil maturation and activation remain largely unexplored.</p>Methods<p>Using single-cell RNA sequencing in a RAG1-deficient chicken model, we mapped heterophil maturation during
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Data Sheet 3_Exploiting RAG1-deficient chickens to construct a single-cell transcriptional atlas of chicken heterophils during inflammation.xlsxIntroduction<p>Avian heterophils naturally lack myeloperoxidase (MPO), making chicken a unique evolutionary model for investigating MPO-independent innate immune strategies. However, the molecular programs governing heterophil maturation and activation remain largely unexplored.</p>Methods<p>Using single-cell RNA sequencing in a RAG1-deficient chicken model, we mapped heterophil maturation during
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 1_Longitudinal single-cell analysis identifies a chemotherapy-suppressed proliferative program associated with adverse prognosis in neuroblastoma.xlsxBackground<p>High-risk neuroblastoma frequently relapses after intensive therapy, but the treatment-associated malignant-neuroblast programs that inform baseline tumor risk remain incompletely defined. We used longitudinal single-cell/single-nucleus RNA-seq data to identify post-treatment transcriptional changes in malignant neuroblasts and evaluated their prognostic relevance in diagnostic bulk R
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Single-cell RNA-seq data from Sakimoto et al, 2024<p dir="ltr">Seurat object (Filtered, processed scRNA-seq data) from Sakimoto et al, BJC Reports, 2024 (https://doi.org/10.1038/s44276-024-00112-3).</p>
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Data Sheet 4_Exploiting RAG1-deficient chickens to construct a single-cell transcriptional atlas of chicken heterophils during inflammation.xlsxIntroduction<p>Avian heterophils naturally lack myeloperoxidase (MPO), making chicken a unique evolutionary model for investigating MPO-independent innate immune strategies. However, the molecular programs governing heterophil maturation and activation remain largely unexplored.</p>Methods<p>Using single-cell RNA sequencing in a RAG1-deficient chicken model, we mapped heterophil maturation during
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Data Sheet 2_Exploiting RAG1-deficient chickens to construct a single-cell transcriptional atlas of chicken heterophils during inflammation.xlsxIntroduction<p>Avian heterophils naturally lack myeloperoxidase (MPO), making chicken a unique evolutionary model for investigating MPO-independent innate immune strategies. However, the molecular programs governing heterophil maturation and activation remain largely unexplored.</p>Methods<p>Using single-cell RNA sequencing in a RAG1-deficient chicken model, we mapped heterophil maturation during
figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 3_Longitudinal single-cell analysis identifies a chemotherapy-suppressed proliferative program associated with adverse prognosis in neuroblastoma.xlsxBackground<p>High-risk neuroblastoma frequently relapses after intensive therapy, but the treatment-associated malignant-neuroblast programs that inform baseline tumor risk remain incompletely defined. We used longitudinal single-cell/single-nucleus RNA-seq data to identify post-treatment transcriptional changes in malignant neuroblasts and evaluated their prognostic relevance in diagnostic bulk R
ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 1_Single-cell profiling of peripheral immune remodeling in BK polyomavirus–associated nephropathy after kidney transplantation.xlsx<p>BK polyomavirus–associated nephropathy (BKPyVAN) remains a major cause of allograft dysfunction after kidney transplantation. To define peripheral immune signatures associated with distinct clinical states of BKPyV infection, we performed single-cell RNA sequencing of peripheral blood mononuclear cells from kidney transplant recipients across three clinical states: stable graft function (n = 1)
ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 4_Single-cell profiling of peripheral immune remodeling in BK polyomavirus–associated nephropathy after kidney transplantation.xlsx<p>BK polyomavirus–associated nephropathy (BKPyVAN) remains a major cause of allograft dysfunction after kidney transplantation. To define peripheral immune signatures associated with distinct clinical states of BKPyV infection, we performed single-cell RNA sequencing of peripheral blood mononuclear cells from kidney transplant recipients across three clinical states: stable graft function (n = 1)
ZivaHub + Deakin Research Online + DMU Figshare2026 · Single-cell RNA sequencing
Image 4_MTHFD1L-associated branched-chain amino acid degradation transcriptional signature represents a conserved metabolic program in Epstein-Barr virus-associated malignancies.jpg<p>Epstein-Barr virus (EBV)-associated malignancies encompass multiple tumor types with distinct tissue origins, yet the extent to which they share conserved metabolic programs remains poorly understood. Here, we performed an integrated cross-cancer transcriptomic analysis of nasopharyngeal carcinoma, EBV-associated gastric cancer, and EBV-associated plasmablastic lymphoma to identify conserved me
ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 1_Patient-aware single-cell analysis of fibrovascular remodeling in a predominantly colorectal cancer immunotherapy cohort.xlsxBackground<p>Cancer-associated fibroblasts (CAFs) and vascular mural cells may shape extracellular matrix organization in colorectal cancer. However, single-cell comparisons are susceptible to unequal cell recovery, ambient RNA, doublets, treatment-stage mixing, and repeated sampling within patients. We investigated fibrovascular remodeling using patients as the inferential unit and distinguished
ZivaHub + Deakin Research Online + DMU Figshare2026 · Single-cell RNA sequencing
Image 5_MTHFD1L-associated branched-chain amino acid degradation transcriptional signature represents a conserved metabolic program in Epstein-Barr virus-associated malignancies.jpg<p>Epstein-Barr virus (EBV)-associated malignancies encompass multiple tumor types with distinct tissue origins, yet the extent to which they share conserved metabolic programs remains poorly understood. Here, we performed an integrated cross-cancer transcriptomic analysis of nasopharyngeal carcinoma, EBV-associated gastric cancer, and EBV-associated plasmablastic lymphoma to identify conserved me
ZivaHub + Deakin Research Online + DMU Figshare2026 · Single-cell RNA sequencing
Image 2_MTHFD1L-associated branched-chain amino acid degradation transcriptional signature represents a conserved metabolic program in Epstein-Barr virus-associated malignancies.jpg<p>Epstein-Barr virus (EBV)-associated malignancies encompass multiple tumor types with distinct tissue origins, yet the extent to which they share conserved metabolic programs remains poorly understood. Here, we performed an integrated cross-cancer transcriptomic analysis of nasopharyngeal carcinoma, EBV-associated gastric cancer, and EBV-associated plasmablastic lymphoma to identify conserved me
ZivaHub + Deakin Research Online + DMU Figshare2026 · Single-cell RNA sequencing
Image 3_MTHFD1L-associated branched-chain amino acid degradation transcriptional signature represents a conserved metabolic program in Epstein-Barr virus-associated malignancies.jpg<p>Epstein-Barr virus (EBV)-associated malignancies encompass multiple tumor types with distinct tissue origins, yet the extent to which they share conserved metabolic programs remains poorly understood. Here, we performed an integrated cross-cancer transcriptomic analysis of nasopharyngeal carcinoma, EBV-associated gastric cancer, and EBV-associated plasmablastic lymphoma to identify conserved me
ZivaHub + Deakin Research Online + DMU Figshare2026 · Single-cell RNA sequencing
Image 1_Patient-aware single-cell analysis of fibrovascular remodeling in a predominantly colorectal cancer immunotherapy cohort.tiffBackground<p>Cancer-associated fibroblasts (CAFs) and vascular mural cells may shape extracellular matrix organization in colorectal cancer. However, single-cell comparisons are susceptible to unequal cell recovery, ambient RNA, doublets, treatment-stage mixing, and repeated sampling within patients. We investigated fibrovascular remodeling using patients as the inferential unit and distinguished
ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 3_Single-cell profiling of peripheral immune remodeling in BK polyomavirus–associated nephropathy after kidney transplantation.xlsx<p>BK polyomavirus–associated nephropathy (BKPyVAN) remains a major cause of allograft dysfunction after kidney transplantation. To define peripheral immune signatures associated with distinct clinical states of BKPyV infection, we performed single-cell RNA sequencing of peripheral blood mononuclear cells from kidney transplant recipients across three clinical states: stable graft function (n = 1)
ZivaHub + Deakin Research Online + DMU Figshare2026 · Single-cell RNA sequencing
Image 3_Patient-aware single-cell analysis of fibrovascular remodeling in a predominantly colorectal cancer immunotherapy cohort.tiffBackground<p>Cancer-associated fibroblasts (CAFs) and vascular mural cells may shape extracellular matrix organization in colorectal cancer. However, single-cell comparisons are susceptible to unequal cell recovery, ambient RNA, doublets, treatment-stage mixing, and repeated sampling within patients. We investigated fibrovascular remodeling using patients as the inferential unit and distinguished
ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Data Sheet 2_MTHFD1L-associated branched-chain amino acid degradation transcriptional signature represents a conserved metabolic program in Epstein-Barr virus-associated malignancies.xlsx<p>Epstein-Barr virus (EBV)-associated malignancies encompass multiple tumor types with distinct tissue origins, yet the extent to which they share conserved metabolic programs remains poorly understood. Here, we performed an integrated cross-cancer transcriptomic analysis of nasopharyngeal carcinoma, EBV-associated gastric cancer, and EBV-associated plasmablastic lymphoma to identify conserved me
ZivaHub + Deakin Research Online + DMU Figshare2026 · Single-cell RNA sequencing
Image 2_Patient-aware single-cell analysis of fibrovascular remodeling in a predominantly colorectal cancer immunotherapy cohort.tiffBackground<p>Cancer-associated fibroblasts (CAFs) and vascular mural cells may shape extracellular matrix organization in colorectal cancer. However, single-cell comparisons are susceptible to unequal cell recovery, ambient RNA, doublets, treatment-stage mixing, and repeated sampling within patients. We investigated fibrovascular remodeling using patients as the inferential unit and distinguished
ZivaHub + Deakin Research Online + DMU Figshare2026 · Single-cell RNA sequencing
Image 1_MTHFD1L-associated branched-chain amino acid degradation transcriptional signature represents a conserved metabolic program in Epstein-Barr virus-associated malignancies.jpg<p>Epstein-Barr virus (EBV)-associated malignancies encompass multiple tumor types with distinct tissue origins, yet the extent to which they share conserved metabolic programs remains poorly understood. Here, we performed an integrated cross-cancer transcriptomic analysis of nasopharyngeal carcinoma, EBV-associated gastric cancer, and EBV-associated plasmablastic lymphoma to identify conserved me
ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Data Sheet 1_RTK–RAS pathway alterations in hepatocellular carcinoma and cholangiocarcinoma: a multicohort genomic and single-cell transcriptomic study.docxObjective<p>To determine whether heterogeneous genomic alterations detected by clinical tumor panels converge on a reproducible pathway-level difference between hepatocellular carcinoma (HCC) and cholangiocarcinoma (CCA), and to examine its transcriptional output, cellular localization, and tumor–stromal coexpression context in public multi-omics cohorts.</p>Methods<p>The institutional cohort comp
ZivaHub + Deakin Research Online + DMU Figshare + HKU DataHub + Swinburne Figshare + DaYta Ya Rona + SUNScholarData + figshare + Loughborough Research Repository + GRANTS Data + UP Research Data Repository2026 · Single-cell RNA sequencing
Table 5_Single-cell profiling of peripheral immune remodeling in BK polyomavirus–associated nephropathy after kidney transplantation.xlsx<p>BK polyomavirus–associated nephropathy (BKPyVAN) remains a major cause of allograft dysfunction after kidney transplantation. To define peripheral immune signatures associated with distinct clinical states of BKPyV infection, we performed single-cell RNA sequencing of peripheral blood mononuclear cells from kidney transplant recipients across three clinical states: stable graft function (n = 1)