Highly efficient vacancy-driven photothermal therapy mediated by ultrathin MnO2 nanosheet

Herein, an ultrathin MnO2 nanosheet has been fabricated by a simplistic hydrothermal process. The high photothermal conversion performance (62.4%) can be attributed to the vacancy in the ultrathin MnO2 nanosheet, as confirmed by the extended Xray absorption fine structure results and the density functional theory calculation, benefiting photoacoustic imaging-guided cancer therapy.

This highly efficient vacancy-induced photothermal therapy has been reported for the first time. As a result, this work demonstrates that this ultrathin MnO2 nanosheet has a potential to construct a nanosystem for imaging-guided cancer therapy.