Data generated from the in vitro gastrointestinal digestion and colonic fermentation of araticum pulp

This dataset compiles information generated from investigating the impact of in vitro gastrointestinal digestion (INFOGEST), transport across Caco-2 cell monolayers, and batch colonic fermentation on the composition, bioaccessibility, bioavailability, metabolism, and biological activities of phenolic compounds from araticum pulp (Annona crassiflora Mart.). The dataset includes total phenolic content (TPC); phytochemical characterization by UHPLC-Q-Orbitrap-MS/MS and HPLC-DAD; antioxidant capacity determined by various in vitro assays; carbohydrate profiles; anti-inflammatory activity in LPS-stimulated RAW 264.7 macrophages; in silico analyses of interactions between phenolic compounds and target proteins involved in the inflammatory response; as well as gut microbiota composition and microbial metabolite production resulting from in vitro colonic fermentation.

This dataset was produced to support studies on functional foods, bioactive compounds, gut health, and inflammation modulation, areas of importance to research in Food Science, Nutrition, among others.