Data · dataset · 2024
RNA SEQ data of mouse AMs and MF treated with LC in vivo
Listed in ScienceDB
AMs and EGFP+-MF derived from fibrotic mouse lung tissues in vivo and divided into the following two groups.: 1.
Description
The control group was treated with solvent (water); 2. Lithium carbonate group was treated with 75 mg/kg lithium carbonate for 3/10 days.
The mouse model of reversible PF was generated by single intratracheal instillation of BLM (3U/kg) in 50 µL of H2O; For therapeutic experiments, mice were i.g. injected with the indicated agents every day beginning at day 14 after BLM challenge for 10 days. AMs were obtained from BALF, EGFP+-MF derived from fibrotic Acta2-EGFP mice. The samples were lysed with Trizol and then total RNA was extracted for RNASEQ sequencing. Sample B1, B5, B7 was CTR in the control group (AMs); Sample LC2, LC3, LC7 was LC in LC treatment group (AMs).
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Sample C1, C3, C4 was CTR in the control group (MF); Sample T1, T2, T3 was LC in LC treatment group (MF).
Links
Where it is published
- DOI doi.org/10.57760/sciencedb.17184 ↗
DOI / persistent id · from scidb cn
Catalogue records · 1
- OAI-PMH record scidb.cn/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=10.57760%2… ↗
metadata API · from scidb cn
Topics
- From keywords
- Earth & Environmental Science · Engineering · Humanities · Life Sciences · Social Science
- Inferred from text
- RNA sequencing 65% · Sequencing 75%
Provenance · 1 source records, 12 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ScienceDB | 10.57760/sciencedb.17184 | 11 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:engineering | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:humanities | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:social-science | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[modality].local:modality:rna-seq | enrichment · scidb cn | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[modality].local:modality:sequencing | enrichment · scidb cn | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/description |
| license | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/rights |
| publication_date | source · scidb cn | connector:scidb_cn@1.0.0 | |
| title | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/title |