Inhibitory effect and mechanism of dihydromyricetin against caudal venous thrombosis in zebrafish-original data

Using 3 dpf MPO-EGFP transgenic zebrafish as the research object, a blank control group, a model group, an aspirin group, and DHM 50, 100, and 200 μ g/mL groups were set up, and each experiment was independently repeated three times. The data includes staining area of red blood cells in the tail vein and heart, thrombus formation rate and inhibition rate, neutrophil fluorescence intensity, relative expression levels of MPO, TNF - α, and IL-6 mRNA, ROS fluorescence value, incidence of intestinal bleeding, and molecular docking binding energy.

The images were analyzed using Image Pro Plus 6.0, and statistical analysis and plotting were performed using GraphPad Prism 9. The data were presented as mean ± standard deviation.