Is it feasible to assess clinical remission in asthma via a customized data extraction approach from a real-world clinical electronic medical records database in Japan? A retrospective real-world study

Additionally, forced expiratory volume in 1 s (FEV₁%)/forced vital capacity and fractional exhaled nitric oxide (FeNO) test frequency were extracted.</p> <p>Of 32 258 eligible patients, only 1.8–3.0%, 0.5–1.5% and 4.5–10.1% had 3- to 18-month ACT, FEV₁% or FeNO data available. Among patients with 3-month ACT data (2.9% [<i>n</i> = 934/32 258]), 98.6% (<i>n</i> = 921/934) had no exacerbations and 81.0% (<i>n</i> = 757/934) had no OCS use.

Among evaluable patients (3-months: 2.9%; 18-months: 3.0%), 41.1% (<i>n</i> = 384/934) met all CR components at 3-months and 69.3% (<i>n</i> = 199/287) at 18-months post-initiation.</p> <p>This study suggests it may be feasible to assess CR using EMR data in Japanese patients with asthma. However, infrequent recording of CR components in clinical practice, particularly ACT and lung function tests, limits availability of EMR data for CR assessments and the potential generalizability of CR findings.</p>