Data · dataset · 2020
Clinical characteristics and histopathological changes of morphea; A single-center, retrospective study of 137 patients
Listed in Teesside University Research Data Repository
Supplemental figure 1.
Description
Clinical variants of morphea: (A) plaque type on the upper back (B) linear (en coup de sabre) type (C) linear type with blaschkoid distribution (D) deep type accompanied with muscle atrophy (E) generalized type which showed isomorphic plaques covering the entire trunk. Supplemental figure 2.
The three patterns of sclerosis in morphea: (A) Top-heavy pattern; moderate to severe sclerosis in the papillary to the superficial reticular dermis, while below the mid dermis is relatively spared. (B) Bottom-heavy pattern; moderate to severe sclerosis below the mid dermis, while papillary to the superficial reticular dermis is relatively spared. (C) Full-thickness pattern; moderate to severe sclerosis throughout the whole dermis.
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(Hematoxylin-eosin stain: x40.) Supplemental figure 3. Histopathological features associated with poor treatment response: (A) Severe degree of sclerosis, which showed extensive fibrosis into the deep dermis and subcutis. (B) Dense inflammatory infiltrates at the dermal-subcutaneous junction and adjacent fat tissue.
(C) Presence of tissue eosinophils. (D) Prominent basal layer hyperpigmentation. (Hematoxylin-eosin stain: A, B and D x100; C x200.) Supplement Table I. Definition and criteria for the extent of histologic sclerosis (global sclerosis score) and the pattern of sclerosis.
(Modified from Walker D et al, JAAD 2017;76:1124-30., and Verrecchia F et al, Rheumatology (Oxford, England) 2007;46:833-41.)
Links
Where it is published
- DOI doi.org/10.17632/7vw66kb7vp.3 ↗
DOI / persistent id · from researchdata tees ac uk
Catalogue records · 1
- OAI-PMH record data.mendeley.com/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Adata… ↗
metadata API · from researchdata tees ac uk
Topics
- From keywords
- Dermatology · Earth & Environmental Science · Engineering · Humanities · Life Sciences · Pathology · Social Science
- Inferred from text
- Tabular 65%
Provenance · 1 source records, 13 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Teesside University Research Data Repository | oai:data.mendeley.com/7vw66kb7vp.3 | 9 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].anzsrc:field:320205 | mapping · researchdata tees ac uk | vocabulary-mapper@1.0.0 | keywords['Dermatology'] |
| concepts[field].anzsrc:field:320220 | mapping · researchdata tees ac uk | vocabulary-mapper@1.0.0 | keywords['Pathology'] |
| concepts[field].local:field:earth-environmental | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:engineering | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:humanities | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:social-science | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[modality].local:modality:tabular | enrichment · researchdata tees ac uk | keyword-concept-rules@1.0.0 | title+description (65%) |
| description | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| title | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/title |