Omics · study · 2026
Aging-induced Suppression of Cirbp Compromises DHODH-Mediated Ferroptosis Defense and Attenuates Hypothermic Cardioprotection during Heart Transplantation [ChIP-seq]
Listed in NCBI GEO
The purpose of this study was to explore the potential mechanism of attenuated hypothermic cardioprotection in the aging donor heart during transplantation and investigate its translational values.
Description
We performed chromatin occupancy of Sp1 profiling analysis using data obtained from chromatin immunoprecipitation-sequencing (ChIP-seq) of LV myocardium from the wild-type rat
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE227nnn/GSE227003 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE227003 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA942906 ncbi.nlm.nih.gov/bioproject/PRJNA942906 ↗
project · from NCBI GEO
- PubMed 38690728 pubmed.ncbi.nlm.nih.gov/38690728 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Genome binding/occupancy profiling by high throughput sequencing · Rattus norvegicus
- From keywords
- Life Sciences
- Inferred from text
- Heart 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE227003 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[anatomy].local:anatomy:heart | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:genome-binding-occupancy-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10116 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |