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Data · dataset · 2024

Data from: effects of phloretin therapy on water and glucose transport during experimental peritoneal dialysis: a dose-response study

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Unwanted glucose absorption remains a major drawback of peritoneal dialysis treatment.

Description

Recently we found that phloretin, a non-selective blocker of faciltative glucose channels (GLUTs), acts to reduce glucose absorption thereby improving osmotic water removal during peritoneal dialysis. Experimental peritoneal dialysis was conducted on fifty healthy Sprague-Dawley rats.

The animals were exposed to glucose-based dialysis fluid containing five different concentrations of phloretin. To determine the plasma-to-dialysate transport, we used radiolabeled 18F-deoxyglucose.

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Basic medicine
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
DataCite10.5061/dryad.2z34tmpvf11 d agoJSON v1
FieldAssertionExtractorEvidence
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concepts[field].fos:basic-medicinesource · DataCiteconnector:datacite@1.0.0
created_datesource · DataCiteconnector:datacite@1.0.0
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