The First Chinese Normative Database for Photoreceptor Cell Metrics Derived from Adaptive Optics Fundus Imaging: A Multi-Center Clinical Study

Each subject undergoes a comprehensive evaluation during the screening period (-7 to 0 days), including demographic data (age, gender, ethnicity, height, weight), vital signs (temperature, pulse, respiration, blood pressure), visual acuity examination (naked and glasses wearing distance vision, using a standard logarithmic visual acuity chart), dominant eye examination, non-contact intraocular pressure measurement, slit lamp microscopy (eyelids, conjunctiva, cornea, anterior chamber, iris, pupil, lens), computerized optometry, optical biometry for axial length measurement (IOLMaster 500/700 or Lenstar), fundus color photography, and frequency-domain optical coherence tomography (OCT, scanning range ≥ 6mm × 6mm).

On the day of the examination (Day 0), the subjects underwent an adaptive optics fundus imaging system (AOSLO, Mona IIa, Nanjing Boshi Medical Technology Co., Ltd.) examination after sufficient pupil dilation, and images of photoreceptor cells in the macular area were collected.