Data · study · 2026
Vitamin C facilitates epidermal keratinization through TET-dependent DNA demethylation in basal keratinocytes
Listed in NCBI GEO
Epidermal keratinization is tightly regulated and associated with epigenetic processes, such as DNA methylation, however, the specific role and mechanisms of TET-mediated DNA demethylation in basal keratinocytes remain unclear.
Description
We analyzed Tet2/3 knockdown-induced transcriptional alterations in newborn rat epidermal keratinocytes, assessed global gene expression profiles. (Microarray)
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE327nnn/GSE327997 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE327997 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1453474 ncbi.nlm.nih.gov/bioproject/PRJNA1453474 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by array · Rattus norvegicus
- From keywords
- Life Sciences
- Inferred from text
- Genetics 69%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE327997 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3105 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (69%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-array | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[organism].NCBITaxon:10116 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |