Table · dataset · 2026
Table 1_Effects of soy and isoflavone interventions on plasma lipid profiles in postmenopausal women: an umbrella review.docx
Listed in figshare and Loughborough Research Repository — shown once because both records carry DOI 10.3389/fnut.2026.1949200.s001
Background<p>Although numerous meta-analyses have investigated the effects of soy and isoflavones on lipid profiles in postmenopausal women, a comprehensive evaluation of this evidence remains lacking.
Description
This umbrella review synthesized existing meta-analyses of randomized controlled trials to assess the certainty of the evidence.</p>Methods<p>We searched PubMed, Web of Science, Embase, and the Cochrane Database for studies published through April 22, 2026.
Methodological quality was evaluated using AMSTAR-2, and evidence certainty was assessed using the GRADE approach.</p>Results<p>Seven meta-analyses comprising 21 associations were included. According to AMSTAR-2, two meta-analyses (29%) demonstrated moderate or high quality. Eighteen associations were supported by evidence of moderate or high certainty according to GRADE.
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Soy protein containing isoflavones and soy isoflavone extracts significantly reduced total cholesterol (MD = −0.12 mmol/L, 95% CI: −0.21 to −0.03). Soy isoflavones reduced low-density lipoprotein cholesterol (SMD = −0.11, 95% CI: −0.21 to −0.01). Furthermore, unfermented soy products significantly increased high-density lipoprotein cholesterol (MD = 0.06 mmol/L, 95% CI: 0.02 to 0.10).</p>Conclusion<p>Specific soy-based interventions, rather than general soy consumption, were associated with beneficial changes in lipid profiles among postmenopausal women.</p>Systematic review registration<p>CRD420251243075.</p>
Links
Where it is published
- DOI doi.org/10.3389/fnut.2026.1949200.s001 ↗
DOI / persistent id · from figshare com
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from figshare com
Topics
- From keywords
- Astronomy & Astrophysics · Chemistry · Chemistry · Computer Science & AI · Computer Science & AI · Earth & Environmental Science · Earth & Environmental Science · Economics & Finance · Economics & Finance · Engineering · Engineering · Humanities · Humanities · Life Sciences · Life Sciences · Materials Science · Mathematics & Statistics · Medicine & Health · Medicine & Health · Ocean & Atmospheric Science · Psychology & Behavioral Science · Social Science · Social Science
- Inferred from text
- Medical biochemistry and metabolomics 72% · Tabular 65%
Provenance · 2 source records, 30 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| figshare | oai:figshare.com:article/33962182 | 9 d ago | JSON v1 |
| Loughborough Research Repository | oai:figshare.com:article/33962182 | 9 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].anzsrc:group:3205 | enrichment · figshare com | taxonomy-embedding@1.0.0 | title+keywords+description (72%) |
| concepts[field].local:field:astronomy | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:engineering | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:engineering | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:humanities | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:humanities | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:materials-science | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:mathematics-statistics | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:ocean-atmospheric | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:psychology-behavioral | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:social-science | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:social-science | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[modality].local:modality:tabular | enrichment · figshare com | keyword-concept-rules@1.0.0 | title+description (65%) |
| description | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/description |
| license | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/rights |
| publication_date | source · figshare com | connector:figshare_com@1.0.0 | |
| title | source · figshare com | connector:figshare_com@1.0.0 | /metadata/dc/title |