Data · dataset · 2026
Si Chen: Association between psychostimulant medication use and cardiovascular disease risk in older adults
Listed in ZivaHub
<p dir="ltr">Objectives: To evaluate the association between psychostimulant use and the risk of cardiovascular disease (CVD) among older adults through a systematic review and meta-analysis.<br>
Description
Methods
Four databases were systematically searched for observational studies. Evidence was summarized using narrative synthesis, with random-effects meta-analyses performed where appropriate.<br>Results: Seven studies involving 263,104 participants from six countries or regions were included. Psychostimulant use was not significantly associated with overall CVD risk.
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Subgroup analyses showed no significant association with myocardial infarction, but significantly increased risks of cerebrovascular events and cardiac arrhythmias.<br>Conclusions: These findings suggest that cardiovascular risk assessment and monitoring should be considered when prescribing psychostimulants to older adults. Further high-quality prospective studies are needed to clarify the cardiovascular safety of psychostimulants and provide stronger evidence to support their rational use in older adults.</p>
Links
Where it is published
- DOI doi.org/10.17608/k6.auckland.33977962.v2 ↗
DOI / persistent id · from zivahub uct ac za
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from zivahub uct ac za
Topics
- From keywords
- Cardiovascular disease · Earth & Environmental Science · Medicine & Health
- Inferred from text
- Disease 75% · Heart 65% · Myocardial infarction 75% · Pharmacology and pharmaceutical sciences 70%
Provenance · 1 source records, 12 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ZivaHub | oai:figshare.com:article/33977962 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[anatomy].local:anatomy:heart | enrichment · zivahub uct ac za | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[disease].local:disease:cardiovascular-disease | mapping · zivahub uct ac za | vocabulary-mapper@1.0.0 | keywords['cardiovascular disease'] |
| concepts[disease].local:disease:disease | enrichment · zivahub uct ac za | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[disease].local:disease:myocardial-infarction | enrichment · zivahub uct ac za | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].anzsrc:group:3214 | enrichment · zivahub uct ac za | taxonomy-embedding@1.1.0 | title+keywords+description (70%) |
| concepts[field].local:field:earth-environmental | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| description | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/description |
| license | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/rights |
| publication_date | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| title | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/title |