Supplemental Sentinel Lymph Node Decision Curve Data

This supplemental data contains the multivariable logistic regression models developed to predict 5-year melanoma specific death with and without sentinel lymph node status, and a supplemental table demonstrating the net benefit provided by sentinel lymph node status at each risk threshold probability for melanoma-specific death among the entire study cohort.

Figures include: 1) Receiver operating curves of models estimating risk for 5-year melanoma-specific death among patients with stage IIB/C cutaneous melanoma with a) thickness and ulceration alone and b) incorporating sentinel lymph node status. 2) Histogram demonstrating distribution of predicted risk among patients with stage IIB/C cutaneous melanoma based upon the Clinicopathologic-Sentinel Lymph Node model. 3) Decision curve analysis demonstrating added net benefit with inclusion of sentinel lymph node status in estimating risk for 5-year melanoma-specific death compared to a model including thickness and ulceration alone among stage IIB/C cutaneous melanoma patients a) <65 and b) ≥65 years of age.