<p>The ARM-like domain adopts “up” or “down” conformations.</p>

Ribbon representations of the “ARM-up” (left) and “ARM-down” (right) states show the spatial relationship between the ARM-like domain (yellow) and the LisH domain (orange). The dimeric twofold symmetry axis is shown to highlight the relative position of the ARM-like domains in these two states. <b>(B)</b> Topology and repeat organization of the ARM-like domain.

Top, topology diagram showing the connectivity of the ARM-like domain. Bottom, individual structures of the 12 AHRs. <b>(C)</b> 12 AHRs assemble into a right-handed helical solenoid. Left, ribbon diagram of the ARM-like domain, rainbow-colored from the N-terminus (blue) to the C-terminus (red).