Data · dataset · 2026
Development and characterisation of hybrid triblock copolymeric nanomicelles for ocular drug delivery
Listed in ZivaHub and Deakin Research Online and DMU Figshare — shown once because both records carry DOI 10.17034/32826179.v1
<p>This thesis investigates the development of positively charged, mucoadhesive hybrid triblock copolymer nanomicelles as an innovative ocular drug delivery system aimed at enhancing the stability, solubility, and corneal retention of curcumin for anti-inflammatory therapy.
Description
Amphiphilic copolymers were synthesized to form nanoscale micellar structures capable of sustained drug release and improved ocular bioavailability.
The nanomicelles exhibited favorable physicochemical properties, high encapsulation efficiency, and stability, along with excellent biocompatibility and ocular tolerability. In vitro, ex vivo, and imaging studies confirmed enhanced corneal penetration and targeted interaction with inflamed ocular tissues, supporting their potential to address key limitations of conventional ocular formulations. Overall, the findings underscore hybrid triblock copolymeric nanomicelles as a promising and scalable platform for effective ocular drug delivery with prolonged therapeutic action and reduced systemic exposure.</p><br><i>Thesis is embargoed until 31 Dec 2028.</i><br>
Links
Where it is published
- DOI doi.org/10.17034/32826179.v1 ↗
DOI / persistent id · from zivahub uct ac za
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from zivahub uct ac za
Topics
- From keywords
- Earth & Environmental Science · Earth & Environmental Science · Earth & Environmental Science
- Inferred from text
- Imaging 75%
Provenance · 3 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ZivaHub | oai:figshare.com:article/32826179 | 12 d ago | JSON v1 |
| Deakin Research Online | oai:figshare.com:article/32826179 | 12 d ago | JSON v1 |
| DMU Figshare | oai:figshare.com:article/32826179 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[modality].local:modality:imaging | enrichment · zivahub uct ac za | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/description |
| license_text | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| publication_date | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| title | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/title |