Data · dataset · 2026
Methods for dosimetric measurement and characterisation of laser-driven ion beams
Listed in ZivaHub and Deakin Research Online and DMU Figshare — shown once because both records carry DOI 10.17034/32635089.v1
The work reported within this PhD thesis aims to address some of the technicalities surrounding dosimetry measurements of ultra-high pulse dose rate beams, in particular those generated through the mechanism of laser-driven acceleration.
Description
Early studies of irradiations performed with these beam modalities have indicated reductions in the normal tissue complication probability for similar levels of tumour control, highlighting the potential to offer marked improvements in such clinical applications.
Novel strategies must be devised that are capable of performing accurate dosimetry measurements of these high-dose beams, especially given the harsh experimental environment created. A spectroscopic routine has been developed and reported that allows the characterisation of laser-driven proton beams through a deconvolution algorithm to derive the energy spectrum incident on a stack of radiochromic films. This tool has been tested through an experimental campaign carried out at Clatterbridge Cancer Centre, with an assessment of its accuracy performed through extensive Monte Carlo modelling.
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A novel strategy for dosimetry measurements of laser-driven proton beams has also been presented in this work. This is based on the use of a small portable graphite calorimeter developed at National Physical Laboratory, with the absorbed dose obtained through measurements of the radiation-induced temperature rise in the system. An experimental investigation was performed using the VULCAN PW laser system at Rutherford Appleton Laboratory, successfully demonstrating the proof of this principle in the first measurements of a calorimeter system to detect the absorbed dose of laser-driven beams.
Through the methods developed for the characterisation and dosimetry of ultra-high dose rate laser-driven beams, suitable solutions are presented for accurate measurement of such modalities, whilst overcoming the challenges typically associated with this particle acceleration regime, in addition to unusable conventional detectors. These steps may represent important ones in the translation of this novel accelerating regime to the applications proposed.<br><br>
Links
Where it is published
- DOI doi.org/10.17034/32635089.v1 ↗
DOI / persistent id · from zivahub uct ac za
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from zivahub uct ac za
Topics
- From keywords
- Earth & Environmental Science · Earth & Environmental Science · Earth & Environmental Science
- Inferred from text
- Cancer 75%
Provenance · 3 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ZivaHub | oai:figshare.com:article/32635089 | 12 d ago | JSON v1 |
| Deakin Research Online | oai:figshare.com:article/32635089 | 12 d ago | JSON v1 |
| DMU Figshare | oai:figshare.com:article/32635089 | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[disease].local:disease:cancer | enrichment · zivahub uct ac za | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:earth-environmental | mapping · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · dro deakin edu au | connector:dro_deakin_edu_au@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| description | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/description |
| license_text | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| publication_date | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | |
| title | source · zivahub uct ac za | connector:zivahub_uct_ac_za@1.0.0 | /metadata/dc/title |