Data · dataset · 2026
<p>Identification of DEGs in pSIOs after LPS treatment.</p>
Listed in DMU Figshare and UCL Research Data Repository — shown once because both records carry DOI 10.1371/journal.pone.0359086.g006
<p>(A) Total number of upregulated and downregulated DEGs (<i>p</i> ≤ 0.05 and |log2 fold-change| ≥ 1).
Description
(B) Top 10 upregulated and downregulated DEGs ranked by fold change. (C) Volcano plot of DEGs with top five genes highlighted.
(D) Heatmap and hierarchical clustering of the top 100 DEGs. RNA sequencing was performed using one pooled RNA sample generated from three organoid wells for each experimental group, resulting in one biological replicate (n = 1) per group. DEG, differentially expressed gene.</p>
Links
Where it is published
- DOI doi.org/10.1371/journal.pone.0359086.g006 ↗
DOI / persistent id · from figshare dmu ac uk
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from figshare dmu ac uk
Topics
- From keywords
- Biochemistry and cell biology · Biochemistry and cell biology · Chemistry · Chemistry · Earth & Environmental Science · Earth & Environmental Science · Genetics · Genetics · Immunology · Immunology · Infectious diseases · Infectious diseases · Life Sciences · Life Sciences · Medicine & Health · Medicine & Health · Microbiology · Microbiology · Research, science and technology policy · Research, science and technology policy
- Inferred from text
- RNA sequencing 75% · Sequencing 75%
Provenance · 2 source records, 27 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| DMU Figshare | oai:figshare.com:article/34048159 | 13 d ago | JSON v1 |
| UCL Research Data Repository | oai:figshare.com:article/34048159 | 13 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].anzsrc:field:320211 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Infectious Diseases'] |
| concepts[field].anzsrc:field:320211 | mapping · figshare dmu ac uk | vocabulary-mapper@1.0.0 | keywords['Infectious Diseases'] |
| concepts[field].anzsrc:field:440710 | mapping · figshare dmu ac uk | vocabulary-mapper@1.0.0 | keywords['Science Policy'] |
| concepts[field].anzsrc:field:440710 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Science Policy'] |
| concepts[field].anzsrc:group:3101 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Cell Biology'] |
| concepts[field].anzsrc:group:3101 | mapping · figshare dmu ac uk | vocabulary-mapper@1.0.0 | keywords['Cell Biology'] |
| concepts[field].anzsrc:group:3105 | mapping · figshare dmu ac uk | vocabulary-mapper@1.0.0 | keywords['Genetics'] |
| concepts[field].anzsrc:group:3105 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Genetics'] |
| concepts[field].anzsrc:group:3107 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Microbiology'] |
| concepts[field].anzsrc:group:3107 | mapping · figshare dmu ac uk | vocabulary-mapper@1.0.0 | keywords['Microbiology'] |
| concepts[field].anzsrc:group:3204 | mapping · figshare dmu ac uk | vocabulary-mapper@1.0.0 | keywords['Immunology'] |
| concepts[field].anzsrc:group:3204 | mapping · rdr ucl ac uk | vocabulary-mapper@1.0.0 | keywords['Immunology'] |
| concepts[field].local:field:chemistry | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · rdr ucl ac uk | connector:rdr_ucl_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| concepts[modality].local:modality:rna-seq | enrichment · figshare dmu ac uk | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[modality].local:modality:sequencing | enrichment · figshare dmu ac uk | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | |
| title | source · figshare dmu ac uk | connector:figshare_dmu_ac_uk@1.0.0 | /metadata/dc/title |