Data · dataset · 2026
Design, Synthesis, and Pharmacological Evaluation of Novel 6-Substituted Benzo[4,5]imidazo[1,2-c]quinazolin-5(6H)-ylacetic Acid Derivatives as Multifunctional Small-Molecule GLP-1R Agonists for Type 2 Diabetes–Alzheimer's Disease Comorbidity
Listed in ScienceDB
This dataset contains the molecular structure, synthetic records, NMR spectra data and pharmacological activity results of a series of novel 6-substituted benzo[4,5]imidazole derivatives.
Description
All compounds were designed, synthesized and characterized in our laboratory. The dataset includes SMILES, melting points, ¹H/¹³C NMR data and in vitro bioassay parameters, which supports the structure-activity relationship study.
The data can be reused for molecular modeling, drug screening and related pharmaceutical research.
Links
Where it is published
- DOI doi.org/10.57760/sciencedb.0125v ↗
DOI / persistent id · from scidb cn
Catalogue records · 1
- OAI-PMH record scidb.cn/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=10.57760%2… ↗
metadata API · from scidb cn
Topics
- From keywords
- Earth & Environmental Science · Engineering · Humanities · Life Sciences · Medicine & Health · Social Science
- Inferred from text
- Disease 75%
Provenance · 1 source records, 11 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| ScienceDB | 10.57760/sciencedb.0125v | 12 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[disease].local:disease:disease | enrichment · scidb cn | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:earth-environmental | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:engineering | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:humanities | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| concepts[field].local:field:social-science | mapping · scidb cn | connector:scidb_cn@1.0.0 | |
| description | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/description |
| license_text | source · scidb cn | connector:scidb_cn@1.0.0 | |
| publication_date | source · scidb cn | connector:scidb_cn@1.0.0 | |
| title | source · scidb cn | connector:scidb_cn@1.0.0 | /metadata/dc/title |