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Data · dataset · 2024

Inosine reverses multidrug resistance in Gram-negative bacteria carrying mobilized RND-type efflux pump gene cluster tmexCD-toprJ

Listed in Teesside University Research Data Repository

To explore the impact of tmexCD1-toprJ1 expression on bacterial metabolomic state, tmexCD1-toprJ1 gene was cloned into a high-copy plasmid, pUC19, to generate pUC19-tmexCD1-toprJ1.

Description

An empty vector without tmexCD1-toprJ1 (pUC19) was included as the control. Subsequently, pUC19-tmexCD1-toprJ1 and pUC19 plasmid was transformed into reference strains K. pneumoniae K6.

Then, we performed metabolomic profiling of tmexCD1-toprJ1-negative and -positive bacteria using liquid chromatography-mass spectrometry (LC-MS).

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From keywords
Earth & Environmental Science
Inferred from text
Mass spectrometry 65%
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Teesside University Research Data Repositoryoai:data.mendeley.com/9xp4k5pb4v.115 h agoJSON v1
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concepts[field].local:field:earth-environmentalmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[modality].local:modality:mass-spectrometryenrichment · researchdata tees ac ukkeyword-concept-rules@1.0.0title+description (65%)
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