Pathogen spectrum analysis of hospitalized children with severe acute respiratory tract infection in Pudong New Area of Shanghai from 2018 to 2023

The virus detection rate was the highest in the ≤1-year-old group (27.44%), significantly higher than that in the 11-15-year-old group (13.73%) (χ2 =17.29, P<0.05). The pathogen detection showed significant seasonal fluctuations, reaching a peak in spring (1-3 months) (32.18%) and a trough in autumn (7-9 months) (16.83%), with significant differences between seasons (χ2=10.40, P<0.05). There were significant changes in the pathogen detection rate between years (χ2=67.91, P<0.05).Conclusion The pathogen spectrum of SARI in hospitalized children in Pudong New Area is complex, with the main pathogens being respiratory syncytial virus, parainfluenza virus, and adenovirus.

Mixed infections exist and the pathogen spectrum composition varies with the seasons. The prevalence of respiratory pathogens shows significant age distribution differences and seasonal dynamic characteristics. It is recommended to establish a seasonal early warning mechanism and strengthen the monitoring of key pathogens.