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Data · dataset · 2022

Islet autoantibody positivity in an adult population with recently diagnosed diabetes in Uganda. S1 Data

Listed in LSHTM Data Compass

Aims: This study aimed to investigate the frequency of islet autoantibody positivity in adult patients with recently diagnosed diabetes in Uganda and its associated characteristics.

Description

Methods

Autoantibodies to glutamic acid decarboxylase-65 (GADA), zinc transporter 8 (ZnT8-A), and tyrosine phosphatase (IA-2A) were measured in 534 adult patients with recently diagnosed diabetes. Islet autoantibody positivity was defined based on diagnostic thresholds derived from a local adult population without diabetes. The socio-demographic, clinical, and metabolic characteristics of islet autoantibody-positive and negative participants were then compared.

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The differences in these characteristics were analysed using the x2 test for categorical data and the Kruskal Wallis test for continuous data. Multivariate analysis was performed to identify predictors of islet autoantibody positivity.

Links

Where it is published

Catalogue records · 1

Topics

Inferred from text
Immunology 74%
Provenance · 1 source records, 9 field assertions
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