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Data · dataset · 2025

Characterizing the NIH Activity and Chronicity Indices in Two Independent Lupus Nephritis Cohorts

Listed in IISH Dataverse

The database contains raw, anonymized demographic data (sex, age, ethnicity) and histological data (number of glomeruli, lupus nephritis class, total NIH AI score, active lesion scores, total NIH CI score, chronic lesion scores) for two patient cohorts, presented in two separate sheets.

Description

Ethnicity data was only available for cohort 2 (Legend: 1: caucasian, 2: afro-caribbean, 3: asian, 4: other). The first cohort contains data of patients from Meyer Children’s Hospital (Florence, Italy) and the University Medical Center of Groningen (Groningen, the Netherlands).

The second cohort contains data of patients from the University College London Hospitals NHS Foundation Trust (London, United Kingdom). This data was used to analyse the distribution of the NIH AI and CI and identify the ‘real world’ ranges of the indices. We also explored their relationship with the histological ISN/RPS classes and evaluate which lesions most significantly contribute to these scores.

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Analyses were performed by our statistician using SAS statistical software version 9.4. A pdf file contains a summary of the statistical analysis.

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Where it is published

Catalogue records · 1

Topics

Inferred from text
Clinical sciences 70%
Provenance · 1 source records, 10 field assertions
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IISH Dataversedoi:10.34894/IZBPIU11 d agoJSON v1
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