Dataset associated with "Water-and energy-efficient dialysate flow optimisation in haemodialysis using a data-driven porous media model"

Here we develop a porous media framework that couples a data-driven modified Ergun equation for dialysate-side pressure loss with solute transport modelling. We use this framework to introduce clearance per pumping power (CPP), a performance metric that quantifies solute removal per unit hydraulic pumping power.

For a modelled PHYLTER® HF 17SD dialyser,<i> </i>CPP is maximised at dialysate-to-blood flow ratios of approximately 1.1 to 0.7, depending on solute and ultrafiltration rate. At a blood flow rate of 300 mL min^-1 and an ultrafiltration rate of 30 mL min^-1, the model predicts that reducing the dialysate flow rate from a typical value of 500 to 280 mL min^-1 would save 48 L of water per session while retaining 93% of the urea clearance; furthermore, maintaining equivalent urea dialysis adequacy (Kt/V) would require only approximately 18 additional minutes in a 4-hour session.