Table · dataset · 2026
Table 1_Effects of exercise on cognitive function in older adults: a systematic review and meta-analysis of the mediating role of sleep.docx
Listed in HKU DataHub and figshare and Loughborough Research Repository — shown once because both records carry DOI 10.3389/fnhum.2026.1949679.s001
Background<p>Sleep disturbances affect nearly half of older adults and are linked to cognitive decline, yet the mechanistic pathways linking exercise to cognitive benefits remain poorly understood.
Description
We hypothesized that sleep quality mediates the exercise–cognition relationship in older adults.</p>Methods<p>We systematically searched PubMed, Web of Science, Cochrane CENTRAL, Embase, and PsycINFO from inception to June 2026 for randomized controlled trials examining structured exercise interventions (≥4 weeks) in adults aged ≥60 years that reported both cognitive and sleep outcomes.
Random-effects meta-analyses and meta-analytic structural equation modeling (MASEM) were used to test the mediation hypothesis. Subgroup analyses examined baseline cognitive status and intervention duration.</p>Results<p>Eight studies (841 participants) were included. Exercise significantly improved cognitive function (SMD = 1.32, 95% CI: 0.70–1.94) and sleep quality (SMD = −1.13, 95% CI: −1.73 to −0.53).
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MASEM confirmed sleep quality as a significant partial mediator, with an indirect effect of β = 0.300 (95% CI: 0.125–0.404), accounting for 50.8% of the total cognitive benefit. The mediation proportion was larger in individuals with mild cognitive impairment (67.6%) than in cognitively healthy older adults (31.9%).</p>Conclusion<p>Sleep quality significantly mediates the exercise–cognition relationship in older adults, accounting for approximately half of the cognitive benefit.
These findings identify sleep as a candidate mechanistic target for optimizing exercise interventions, though larger mediation-designed trials are needed to confirm these exploratory estimates.</p>
Links
Where it is published
- DOI doi.org/10.3389/fnhum.2026.1949679.s001 ↗
DOI / persistent id · from datahub hku hk
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from datahub hku hk
Topics
- From keywords
- Astronomy & Astrophysics · Chemistry · Chemistry · Computer Science & AI · Computer Science & AI · Earth & Environmental Science · Earth & Environmental Science · Earth & Environmental Science · Economics & Finance · Economics & Finance · Engineering · Engineering · Humanities · Humanities · Life Sciences · Life Sciences · Life Sciences · Materials Science · Mathematics & Statistics · Medicine & Health · Medicine & Health · Ocean & Atmospheric Science · Psychology & Behavioral Science · Psychology & Behavioral Science · Psychology & Behavioral Science · Social Science · Social Science
- Inferred from text
- Sports science and exercise 70% · Tabular 65%
Provenance · 3 source records, 34 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| HKU DataHub | oai:figshare.com:article/34008153 | 10 d ago | JSON v1 |
| figshare | oai:figshare.com:article/34008153 | 9 d ago | JSON v1 |
| Loughborough Research Repository | oai:figshare.com:article/34008153 | 9 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · datahub hku hk | connector:datahub_hku_hk@1.0.0 | |
| concepts[field].anzsrc:group:4207 | enrichment · datahub hku hk | taxonomy-embedding@1.0.0 | title+keywords+description (70%) |
| concepts[field].local:field:astronomy | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:chemistry | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:computer-science-ai | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · datahub hku hk | connector:datahub_hku_hk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:earth-environmental | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:economics-finance | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:engineering | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:engineering | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:humanities | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:humanities | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · datahub hku hk | connector:datahub_hku_hk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:materials-science | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:mathematics-statistics | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:ocean-atmospheric | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:psychology-behavioral | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:psychology-behavioral | mapping · datahub hku hk | connector:datahub_hku_hk@1.0.0 | |
| concepts[field].local:field:psychology-behavioral | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[field].local:field:social-science | mapping · figshare com | connector:figshare_com@1.0.0 | |
| concepts[field].local:field:social-science | mapping · repository lboro ac uk | connector:repository_lboro_ac_uk@1.0.0 | |
| concepts[modality].local:modality:tabular | enrichment · datahub hku hk | keyword-concept-rules@1.0.0 | title+description (65%) |
| description | source · datahub hku hk | connector:datahub_hku_hk@1.0.0 | /metadata/dc/description |
| license | source · datahub hku hk | connector:datahub_hku_hk@1.0.0 | /metadata/dc/rights |
| publication_date | source · datahub hku hk | connector:datahub_hku_hk@1.0.0 | |
| title | source · datahub hku hk | connector:datahub_hku_hk@1.0.0 | /metadata/dc/title |