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Data · dataset · 2018

TBI and traumatic endotheliopathy

Listed in Teesside University Research Data Repository

Hypothesis: head injury can lead to EoT and that the presence of severe TBI in combination with polytrauma potentiates glycocalyx breakdown.

Description

We expected that patients with both TBI and polytrauma would more frequently have EoT than would patients with either TBI alone or polytrauma alone. 1. Aim 1: To determine the frequency of EoT in TBI patients. 2.

Aim 2: to evaluate how the breakdown of the glycocalyx and the presence of EoT affect outcome in the context of TBI. Prospective observational study. Main biomarker: syndecan-1 Other EoT biomarkers: sTM, adrenaline, noradrenaline.

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EoT= syndecan-1 >40 ng/ml

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Where it is published

Catalogue records · 1

Topics

Provenance · 1 source records, 6 field assertions
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Teesside University Research Data Repositoryoai:data.mendeley.com/svt33j8cyz.117 h agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
concepts[field].local:field:earth-environmentalmapping · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
descriptionsource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0/metadata/dc/description
licensesource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0/metadata/dc/rights
publication_datesource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0
titlesource · researchdata tees ac ukconnector:researchdata_tees_ac_uk@1.0.0/metadata/dc/title