Prognostic value of d-dimer across Four Populations of Critically Ill Patients (Pulmonary Embolism, Influenza A pneumonia, COVID-19 and Septic Shock) Dataset

The present study aims to evaluate the performance of d-dimer as a prognostic biomarker across four different disease populations of critically ill patients: COVID-19, Influenza A pneumonia, septic shock and pulmonary embolism. We hypothesize that patients with poorer outcomes will have higher d-dimer levels, thus suggesting that elevated d-dimer is a significant risk factor for 90-day mortality.

This single-center, observational, prospective study enrolled adult critically ill patients admitted to the Intensive Care Unit (ICU) of a tertiary care university hospital in Spain (Hospital Universitari de Bellvitge), between 2000 and 2021, presenting with pulmonary embolism, severe influenza A pneumonia, severe COVID-19 pneumonia or septic shock with bacteriemia. A total of 124 patients were enrolled in this study: 26 patients with pulmonary embolism, 27 patients with influenza A pneumonia, 27 patients with COVID-19 and 44 patients with septic shock.