Data for Structural studies suggest aggregation as one of the modes of action for teixobactin

Overall, our study provides several new clues to teixobactin’s modes of action.<br><br>The data directories contain raw NMR data used in the Oster et al. Chemical Science manuscript entitled “Structural studies suggest aggregation as one of the modes of action for teixobactin”. The directory called “solid-state” contains solid state NMR data on a sedimented complex of [U-13C,15N]teixobactin with Gram-negative lipid II in DPC micelles.

The directory called “solution-state” contains solution NMR data on various samples. 13C15N_txb_aq - indicates data on a saturated aqueous solution of [U-13C,15N]teixobactin 13C15N_txb_dpc - indicated data on [U-13C,15N]teixobactin in DPC micelles 13C15N_txb_dpc_l2 - indicates data on [U-13C,15N]teixobactin in DPC micelles in a presence of Gram-negative lipid II 13C15N_txb_l2 - indicates data on [U-13C,15N]teixobactin in a presence of Gram-positive lipid II in aqueous solution For the detailed information on conditions, please, refer to the manuscript.