Data · dataset · 2025
The PREVENT-COVID in Seniors Study: PRospEctiVe EvaluatioN of immuniTy after COVID-19 vaccines in Seniors [PREVENT-COVID-19, study data contributed to the CITF Databank]
Listed in Borealis
Description
Background
There is evidence that suggests that vaccines are effective against infection, but it is unclear how age and certain antibodies from previous infections influence their level of effectiveness. Aims of the CITF-funded study: This study aimed to compare short-term and long-term immune responses to COVID-19 vaccines among older adults and seniors. Specifically, they aimed to compare the antibody levels, quantity, and function after vaccination by vaccine type and age.
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Methods
This cohort study enrolled participants in British Columbia who were receiving their first or second dose of the BNT162b2 (Pfizer), mRNA-1273 (Moderna), or ChAdOx1-S COVID-19 vaccine and over the age of 19, pivoting to oversampling older adults (50+) to address high-priority knowledge gaps. Participants answered an online questionnaire at baseline and provided a blood sample via DBS or venipuncture at baseline and at each follow up (7 times at regular intervals).
Contributed dataset contents: The datasets include 772 participants who completed baseline surveys between February 2021 and May 2022. 96% of these participants gave one or more blood samples between February 2021 and June 2023. A total of 3564 samples were collected. Variables include data in the following areas of information: demographics (date of birth, sex, gender, ethnicity), general health (weight and height, flu vaccine, medical conditions), SARS-CoV-2 vaccination, and serology (antibodies against SARS-CoV-2 RBD, nucleocapsid, and spike proteins).
Links
Where it is published
- Dataverse dataset page borealisdata.ca/dataset.xhtml?persistentId=doi%3A10.5683%2FSP3%2FKHJS63 ↗
landing page · from borealisdata ca
- DOI doi.org/10.5683/sp3/khjs63 ↗
DOI / persistent id · from borealisdata ca
Catalogue records · 1
- Dataverse API borealisdata.ca/api/datasets/:persistentId/?persistentId=doi%3A10.5683%2FSP3%2… ↗
metadata API · from borealisdata ca
Topics
- Stated by source
- Medicine, Health and Life Sciences
- From keywords
- Life Sciences · Medicine & Health
- Inferred from text
- Longitudinal study 65%
Provenance · 1 source records, 10 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Borealis | doi:10.5683/SP3/KHJS63 | 11 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| concepts[field].dataverse_subject:medicine-health-and-life-sciences | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | /subjects |
| concepts[field].local:field:life-sciences | mapping · borealisdata ca | connector:borealisdata_ca@1.0.0 | /subjects |
| concepts[field].local:field:medicine-health | mapping · borealisdata ca | connector:borealisdata_ca@1.0.0 | /subjects |
| concepts[method].local:method:longitudinal-study | enrichment · borealisdata ca | keyword-concept-rules@1.0.0 | title+description (65%) |
| created_date | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | |
| description | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | /description |
| publication_date | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | |
| title | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | /name |
| updated_date | source · borealisdata ca | connector:borealisdata_ca@1.0.0 | |
| version_label | source · borealisdata ca | connector:borealisdata_ca@1.0.0 |