Constarium
← Search

Data · dataset · 2011

Data from: Optimal lineage principle for age-structured populations

Listed in DataCite

We present a formulation of branching and aging processes that allows distributions along lineages to be studied within populations, and provides a new interpretation of classical results in the theory of aging.

Description

We establish a variational principle for the stable age distribution along lineages. Using this optimal lineage principle, we show that the response of a population’s growth rate to age-specific changes in mortality and fecundity – a key quantity which was first calculated by Hamilton – is given directly by the age distribution along lineages.

We apply our method also to the Bellman-Harris process, in which both mother and progeny are rejuvenated at each reproduction event, and show that this process can be mapped to the classic aging process such that age statistics in the population and along lineages are identical. Our approach provides both a theoretical framework for understanding the statistics of aging in a population, and a new method of analytical calculations for populations with age structure.

Read the rest (1 more)

We discuss generalizations for populations with multiple phenotypes, and more complex aging processes. We also provide a first experimental test of our theory applied to bacterial populations growing in a microfluidics device.

Links

Topics

Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
DataCite10.5061/dryad.6mj2213 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · DataCiteconnector:datacite@1.0.0/data/attributes/rightsList
byte_sizesource · DataCiteconnector:datacite@1.0.0
concepts[field].anzsrc:field:310404enrichment · DataCitetaxonomy-embedding@1.1.0title+keywords+description (79%)
descriptionsource · DataCiteconnector:datacite@1.0.0/data/attributes/descriptions
licensesource · DataCiteconnector:datacite@1.0.0/data/attributes/rightsList
publication_datesource · DataCiteconnector:datacite@1.0.0/data/attributes/dates
titlesource · DataCiteconnector:datacite@1.0.0/data/attributes/titles/0/title
version_labelsource · DataCiteconnector:datacite@1.0.0