Data · study · 2026
Alcohol Withdrawal Is Associated with Altered PCBP1 RNA Binding in the Hippocampus
Listed in NCBI GEO
Withdrawal from chronic alcohol exposure disrupts brain gene expression and RNA splicing programs.
Description
The multifunctional RNA-binding protein PCBP1 has been previously implicated in RNA alternative splicing in the hippocampus during withdrawal from chronic alcohol (ethanol) exposure. However, the transcriptome-wide RNA targets associated with PCBP1 during ethanol withdrawal are not known.
Here, we generated a map of PCBP1 RNA binding in the hippocampus of male and female rats following a 24-hour withdrawal from chronic ethanol exposure using RNA immunoprecipitation and sequencing (RIP-Seq) with an antibody to PCBP1
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE333nnn/GSE333698 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE333698 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1472068 ncbi.nlm.nih.gov/bioproject/PRJNA1472068 ↗
project · from NCBI GEO
Topics
- Stated by source
- Other · Rattus norvegicus
- From keywords
- Life Sciences
- Inferred from text
- Sequencing 75%
Provenance · 1 source records, 8 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE333698 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:other | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:sequencing | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[organism].NCBITaxon:10116 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |