COVID-19 Infection and Immunity in Residents of Long-term Care Facilities [ C19-IIRLTF, study data contributed to the CITF Databank]

Methods

This cohort study recruited residents from participating long-term care and retirement home across Ontario through invitations from research coordinators. Study visits occurred at participants’ first dose and second dose of the COVID-19 vaccine, and then 3 weeks, 3 months, 6 months, 9, and 12 months post- second dose. For those who got a third dose, follow up was done 3 weeks, 3 months, and 6 months after their third dose.

Staff, essential visitors, and resident participants were followed up every week or per visit for saliva surveillance active COVID infection . A DBS whole blood sample was given at enrolment and at each follow up for serology testing. Contributed dataset contents: The datasets include 1261 participants who completed baseline surveys between January 2021 and July 2023. 90% of participants gave one or more blood samples between April 2021 and April 2023 for analysis.

A total of 6078 samples were collected. Variables include data in the following areas of information: demographics (date of birth, sex, race-ethnicity, indigeneity), general health (weight and height, smoking, flu vaccination, chronic conditions), SARS-CoV-2 outcomes (positive test results, hospitalizations), SARS-CoV-2 vaccination, and serology (IgA, IgG, and IgM against SARS-CoV-2 receptor-binding domain (RBD) and spike (S) protein).