Data · dataset · 2026
<p>Sand fly specimen identification results.</p>
Listed in NCL Data
<div> <p>Background</p><p>Leishmaniasis is a severe parasitic disease transmitted by sand fly bites. <i>Phlebotomus sergenti</i> is a principal vector of <i>Leishmania tropica</i>, causing anthroponotic cutaneous leishmaniasis (ACL) across the Mediterranean, North Africa, South Asia, and West Asia.
Description
The Xinjiang Uygur Autonomous Region, located in northwestern China, is a well-recognized endemic focus of visceral leishmaniasis (VL), with sporadic cutaneous leishmaniasis cases also documented in the region.
Nevertheless, <i>Ph. sergenti</i> has never been reported in China prior to this study.</p> <p>Methodology/principal findings</p><p>Field investigations were carried out in Artux City (July 2023) and Akto County (August–September 2024), Kizilsu Kirghiz Autonomous Prefecture, Xinjiang Uygur Autonomous Region. Sand flies were collected using light traps in livestock pens and residential areas. A total of 2,013 sand fly specimens were collected and 319 of them were identified through morphological examination of the pharynx, spermathecae, and genitalia, combined with molecular analysis of mitochondrial cytochrome c oxidase subunit I (COI) and cytochrome b (Cyt b) genes.
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Among the identified specimens, 145 specimens were identified as <i>Ph. sergenti</i> (36 from Artux City, 109 from Akto County), representing the first record of this species in China. Phylogenetic analysis based on COI and Cyt b sequences showed that Chinese <i>Ph. sergenti</i> populations clustered with those from neighboring countries (e.g., Afghanistan), with no significant genetic differentiation between the two sampling localities.
Metagenomic screening of pooled samples revealed the presence of Wolbachia endosymbionts but no detection of <i>Leishmania</i> spp., <i>Trypanosoma</i> spp. or <i>Bartonella</i> spp. in the collected <i>Ph. sergenti</i> specimens.</p> <p>Conclusions/significance</p><p>This study represents the first confirmed record of <i>Ph. sergenti</i> in China, filling a critical gap in the distribution map of this medically important sand fly species.
The occurrence of <i>Ph. sergenti</i> at the China—Kyrgyzstan border region suggests potential transboundary dispersal of this vector and underscores the need for enhanced surveillance and cross-border collaborative efforts to monitor the spread of leishmaniasis and other vector-borne diseases in Central Asia.</p></div>
Links
Where it is published
- DOI doi.org/10.1371/journal.pntd.0014726.t002 ↗
DOI / persistent id · from data ncl ac uk
Catalogue records · 1
- OAI-PMH record api.figshare.com/v2/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Af… ↗
metadata API · from data ncl ac uk
Topics
- From keywords
- Biochemistry and cell biology · Bioinformatics and computational biology · Cancer · Earth & Environmental Science · Ecology · Infectious diseases · Life Sciences · Medicine & Health
- Inferred from text
- Disease 75%
Provenance · 1 source records, 14 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCL Data | oai:figshare.com:article/34074357 | 25 h ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · data ncl ac uk | connector:data_ncl_ac_uk@1.0.0 | |
| concepts[disease].local:disease:cancer | mapping · data ncl ac uk | vocabulary-mapper@1.0.0 | keywords['Cancer'] |
| concepts[disease].local:disease:disease | enrichment · data ncl ac uk | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].anzsrc:field:320211 | mapping · data ncl ac uk | vocabulary-mapper@1.0.0 | keywords['Infectious Diseases'] |
| concepts[field].anzsrc:group:3101 | mapping · data ncl ac uk | vocabulary-mapper@1.0.0 | keywords['Cell Biology'] |
| concepts[field].anzsrc:group:3102 | mapping · data ncl ac uk | vocabulary-mapper@1.0.0 | keywords['Computational Biology'] |
| concepts[field].anzsrc:group:3103 | mapping · data ncl ac uk | vocabulary-mapper@1.0.0 | keywords['Ecology'] |
| concepts[field].local:field:earth-environmental | mapping · data ncl ac uk | connector:data_ncl_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · data ncl ac uk | connector:data_ncl_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · data ncl ac uk | connector:data_ncl_ac_uk@1.0.0 | |
| description | source · data ncl ac uk | connector:data_ncl_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · data ncl ac uk | connector:data_ncl_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · data ncl ac uk | connector:data_ncl_ac_uk@1.0.0 | |
| title | source · data ncl ac uk | connector:data_ncl_ac_uk@1.0.0 | /metadata/dc/title |