Omics · study · 2026
High-Cell-Density Fed-Batch Fermentation of PG-PANC-AC Strain for Progesterone Production
Listed in NCBI GEO
We metabolically engineered Saccharomyces cerevisiae BY4742 to construct strain PG-PANC-AC, which can de novo synthesize progesterone using ethanol as a carbon source.
Description
To investigate the changes in gene transcription levels of this strain at different time points during progesterone production in a 5 L fermenter system, we performed RNA-seq analysis on collected samples.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE308nnn/GSE308919 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308919 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1333401 ncbi.nlm.nih.gov/bioproject/PRJNA1333401 ↗
project · from NCBI GEO
- PubMed 42705497 pubmed.ncbi.nlm.nih.gov/42705497 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Saccharomyces cerevisiae
- From keywords
- Life Sciences
- Inferred from text
- Fermentation 76% · RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE308919 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:field:310603 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (76%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:4932 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |