Omics · study · 2026
The study on the mechanism of AalpiRNA-58 in influencing midgut digestion and ovarian development in Aedes albopictus
Listed in NCBI GEO
The reproductive physiology of female mosquitoes is closely associated with the ingestion of vertebrate blood, a biological characteristic that not only provides essential nutritional support for the maturation of oocytes but also plays a crucial role in the transmission of vector-borne diseases.
Description
This study focuses on female Aedes albopictus individuals, with particular attention to the highly expressed piRNA molecules within their bodies.
We aim to explore the expression patterns and molecular regulatory mechanisms of these non-coding RNAs during midgut digestion. Based on the female-specific piRNA expression profiles obtained from previous high-throughput screening, we systematically investigated their biological functions, emphasizing the regulatory roles and molecular mechanisms of piRNAs in the midgut digestive system. By deciphering the molecular regulatory network of piRNAs in the digestive and metabolic processes, this research provides new directions for the screening of molecular targets in mosquito sterility techniques, while offering theoretical foundations and innovative insights for the development of novel vector control strategies.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE308nnn/GSE308483 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE308483 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1330744 ncbi.nlm.nih.gov/bioproject/PRJNA1330744 ↗
project · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing
- From keywords
- Life Sciences
- Inferred from text
- Zoology 71%
Provenance · 1 source records, 7 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE308483 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[field].anzsrc:group:3109 | enrichment · NCBI GEO | taxonomy-embedding@1.1.0 | title+keywords+description (71%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |