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Differential gene expression in Toxoplasma gondii-infected cells with modulated IFITM2/3 expression

Listed in NCBI GEO

Transcriptome sequencing (RNA-seq) was performed to investigate the global gene expression changes in host cells following Toxoplasma gondii infection, with a focus on the regulatory roles of interferon-induced transmembrane proteins 2 and 3 (IFITM2/3).

Description

Host cells were transfected with IFITM2 or IFITM3 overexpression vectors or empty vector controls, then infected with Toxoplasma gondii. Uninfected cells with corresponding vector transfections were included as controls.

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From keywords
Life Sciences
Inferred from text
Genetics 69% · RNA sequencing 65% · Sequencing 75%
Provenance · 1 source records, 9 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE33579013 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].anzsrc:group:3105enrichment · NCBI GEOtaxonomy-embedding@1.1.0title+keywords+description (69%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title