Omics · study · 2026
Transcriptome profile of liver and tumor tissues from CDA/HFD-fed rats treated with aripiprazole
Listed in NCBI GEO
Metabolic dysfunction-associated steatotohepatitis (MASH) is a rapidly growing global health problem that leads to lethal complications such as liver cirrhosis and cancer.
Description
Bulk RNA-Seq was performed on liver and tumor tissues from Wistar rats fed a choline-deficient L-amino acid-defined high-fat diet (CDA/HFD) or a normal chow diet, and treated with aripiprazole or vehicle (DMSO), to evaluate their potential chemopreventive effects against hepatocellular carcinoma.
Links
Get the data
- GEO FTP directory ftp.ncbi.nlm.nih.gov/geo/series/GSE315nnn/GSE315143 ↗
download · from NCBI GEO
Where it is published
- GEO accession page ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE315143 ↗
landing page · from NCBI GEO
Documentation and papers
- PRJNA1395049 ncbi.nlm.nih.gov/bioproject/PRJNA1395049 ↗
project · from NCBI GEO
- PubMed 41838879 pubmed.ncbi.nlm.nih.gov/41838879 ↗
publication · from NCBI GEO
Topics
- Stated by source
- Expression profiling by high throughput sequencing · Rattus norvegicus
- From keywords
- Life Sciences
- Inferred from text
- Cancer 75% · RNA sequencing 65%
Provenance · 1 source records, 9 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| NCBI GEO | GSE315143 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[disease].local:disease:cancer | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (75%) |
| concepts[field].local:field:life-sciences | mapping · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencing | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /gdstype |
| concepts[modality].local:modality:rna-seq | enrichment · NCBI GEO | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[organism].NCBITaxon:10116 | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /taxon |
| description | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /summary |
| publication_date | source · NCBI GEO | connector:ncbi_geo@1.0.0 | |
| title | source · NCBI GEO | connector:ncbi_geo@1.0.0 | /title |