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Data · dataset · 2026

Figure 2 from Improving Long-Read Somatic Structural Variant Calling with Pangenome and <i>De Novo</i> Personal Genome Assembly

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<p>Somatic SV calling on matched COLO829 tumor–normal cell lines. <b>A–D,</b> Metrics on <i>de novo</i> assembly-based filtering. <b>E–H,</b> Metrics on pangenome-based filtering. <b>A</b> and <b>E,</b> Number of FP and TP SV calls (<b>C</b> and <b>G</b>) from PacBio HiFi data at different cutoffs on supporting reads.

Description

The solid bars correspond to SV calls still observed in the alignment against the COLO829BL (derived from blood) assembly, whereas the shaded bars correspond to calls filtered by the assembly.

The horizontal line gives the number of SV calls from Valle-Inclan and colleagues (<a target="_blank" href="#bib22">22</a>), which are taken as ground truth. <b>B</b> and <b>F,</b> Number of FP and TP calls (<b>D</b> and <b>H</b>) from ONT reads.</p>

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ZivaHuboai:figshare.com:article/340228708 d agoJSON v1
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