Identification and evaluation of a bioactive peptide QUB-2560 from the skin secretion of <i>Odorrana andersonii</i>

Given the widespread and prolonged use of conventional antibiotics globally, antibiotic resistance has inevitably become a pressing concern. As a result, the exploration of alternative solutions like antimicrobial peptides (AMP) has gained significant attention.

Some amphibian skin secretes peptides with various biological activities. My research aims to contribute to this critical area of study.<br><br>In particular, some positively charged, α-helical and amphiphilic peptides are more likely to have good antibacterial activity. In the present study, an antimicrobial peptide, named QUB-2560, was isolated from the skin secretions of <i>Odorrana andersonii</i> and was found to exhibit a wide range of antimicrobial activity against Gram-negative bacteria, Gram-positive bacteria and fungi.