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Excel · study · 2026

Transcriptomic response to PE-induced hypertrophy upon RBP1 knockdown in neonatal rat cardiomyocytes

Listed in NCBI GEO

This dataset provides a comprehensive transcriptomic profile to investigate the role of Retinol Binding Protein 1 (RBP1) in phenylephrine (PE)-induced cardiac hypertrophy.

Description

RBP1 acts as a central homeostatic regulator of intracellular retinol , yet its specific function in pathological mechanisms of hypertrophic cardiomyocytes remains incompletely defined. To elucidate this, we performed RNA sequencing on neonatal rat cardiomyocytes (NRCMs) subjected to RBP1 knockdown followed by PE stimulation.

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Stated by source
Expression profiling by high throughput sequencing · Rattus norvegicus
From keywords
Life Sciences
Inferred from text
Heart 65% · RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 10 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE31387614 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[anatomy].local:anatomy:heartenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (65%)
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[organism].NCBITaxon:10116source · NCBI GEOconnector:ncbi_geo@1.0.0/taxon
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title