Data · dataset · 2026
Acute Undifferentiated Leukemia
Listed in Teesside University Research Data Repository
This dataset fills a critical gap in published AUL evidence: prior studies only document venetoclax–azacitidine dual therapy, while no public clinical data exists for the triple regimen (azacitidine + venetoclax + sorafenib) in patients with dual FLT3 missense mutations.
Description
All uploaded tables contain granular cycle-by-cycle drug doses, early drug discontinuation timelines and full supportive medication records (G-CSF, eltrombopag, anti-infectives), details condensed within the original manuscript.
Researchers may reuse this dataset for two core analyses: Compare this case’s unique immunophenotype with MPAL/AML-M0 using the full flow cytometry panel; Pool the FLT subclonal mutation data with existing cohorts to analyze outcomes of non-ITD FLT3 variants. Serial MRD records offer real-world reference for MRD-guided dose de-escalation in elderly unfit leukemia patients. All images have been fully de-identified: hospital watermarks, specimen barcodes and sampling timestamps are cropped completely.
Read the rest (3 more)
No data can be cross-matched to inpatient archives, fully complying with institutional ethics rules and the Declaration of Helsinki. The CC-BY 4.0 license allows non-commercial academic reuse, provided users cite both the original manuscript and this dataset DOI. Key interpretative reminders: Permanent megakaryocyte loss is a combined toxic effect of three myelosuppressive agents, not sorafenib alone.
Readers must differentiate transient post-cycle cytopenia from irreversible marrow hypoplasia shown on follow-up bone marrow slides. Restrictions apply to raw NGS fastq files and full electronic medical records per local human genetic regulations. Researchers needing unprocessed sequencing data must submit a formal request with institutional ethical certification and a non-commercial data use agreement to the corresponding author.
Any attempt to trace patient identity or utilize these data for commercial research is prohibited.
Links
Where it is published
- DOI doi.org/10.17632/dm5jj4s7z3.1 ↗
DOI / persistent id · from researchdata tees ac uk
Catalogue records · 1
- OAI-PMH record data.mendeley.com/oai?verb=GetRecord&metadataPrefix=oai_dc&identifier=oai%3Adata… ↗
metadata API · from researchdata tees ac uk
Topics
- From keywords
- Earth & Environmental Science · Engineering · Humanities · Life Sciences · Medical genetics · Medicine & Health · Social Science
- Inferred from text
- Image 65% · Sequencing 75%
Provenance · 1 source records, 14 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| Teesside University Research Data Repository | oai:data.mendeley.com/dm5jj4s7z3.1 | 10 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].anzsrc:field:320213 | mapping · researchdata tees ac uk | vocabulary-mapper@1.0.0 | keywords['Medical Genetics'] |
| concepts[field].local:field:earth-environmental | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:engineering | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:humanities | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:life-sciences | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:medicine-health | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[field].local:field:social-science | mapping · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| concepts[modality].local:modality:image | enrichment · researchdata tees ac uk | keyword-concept-rules@1.0.0 | title+description (65%) |
| concepts[modality].local:modality:sequencing | enrichment · researchdata tees ac uk | keyword-concept-rules@1.0.0 | title+description (75%) |
| description | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/description |
| license | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/rights |
| publication_date | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | |
| title | source · researchdata tees ac uk | connector:researchdata_tees_ac_uk@1.0.0 | /metadata/dc/title |