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Omics · study · 2026

Transcriptome analysis of three Bacillus cereus strains comparing non-conditioned growth medium (nk) with conditioned (k; pre-incubated with CaCo-2 cells), accomplished by RNA sequencing

Listed in NCBI GEO

Enteropathogenic Bacillus cereus can cause toxico-infections manifesting in diarrhea and abdominal pain.

Description

It is still not completely understood why individual isolates differ in enterotoxin production and pathogenicity, and which signals trigger toxicity in the host environment. The overall transcriptional response of three formerly well-characterized strains to a simulated intestinal environment was assessed in the present study.

Two high toxic strains F837/76 = MHI 1505 and NVH 0075-95 = MHI 3053, and one low toxic strain RIVM BC90 = MHI 3178 were investigated.

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From keywords
Life Sciences
Inferred from text
RNA sequencing 75% · Sequencing 75%
Provenance · 1 source records, 8 field assertions
SourceKeyLast seenRaw
NCBI GEOGSE28423712 d agoJSON v1
FieldAssertionExtractorEvidence
access_levelsource · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[field].local:field:life-sciencesmapping · NCBI GEOconnector:ncbi_geo@1.0.0
concepts[method].geo_series_type:expression-profiling-by-high-throughput-sequencingsource · NCBI GEOconnector:ncbi_geo@1.0.0/gdstype
concepts[modality].local:modality:rna-seqenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
concepts[modality].local:modality:sequencingenrichment · NCBI GEOkeyword-concept-rules@1.0.0title+description (75%)
descriptionsource · NCBI GEOconnector:ncbi_geo@1.0.0/summary
publication_datesource · NCBI GEOconnector:ncbi_geo@1.0.0
titlesource · NCBI GEOconnector:ncbi_geo@1.0.0/title