Estimation of femoral loads for bone remodelling simulation using subject-specific musculoskeletal modelling

Markerless motion capture with OpenCap was compared with an optical motion-capture reference system (MoCap).</p><p dir="ltr"><br></p><p dir="ltr">FOLDER STRUCTURE<br><u>Data/MarkerData</u></p><p dir="ltr">Three-dimensional marker trajectories in OpenSim .trc format.</p><ul><li>MoCap/: marker trajectories obtained using the optical motion-capture system. static.trc contains the static calibration trial.</li><li>OpenCap/: marker trajectories reconstructed from the two video views. neutral.trc contains the neutral-pose recording used for model scaling.</li></ul><p dir="ltr"><u>Data/OpenSimData</u><br>OpenSim models, kinematics, and musculoskeletal simulation results.</p><p dir="ltr">MoCap/</p><ul><li>Kinematics/: joint kinematics calculated from the MoCap marker trajectories.</li><li>Model/: generic and subject-scaled OpenSim models and the corresponding scaling and marker-set files.</li></ul><p dir="ltr">OpenCap/</p><ul><li>Kinematics/: OpenCap joint kinematics for all recorded movement trials.</li><li>Model/: OpenSim models used during the OpenCap processing and dynamic simulations.

The directory also contains the associated body geometries in .vtp and .stl format.</li><li>Dynamics/[trial]/: dynamically consistent musculoskeletal simulation results for each successfully processed trial:<br><b>kinematics_activations_[trial]_.mot</b>: tracked joint kinematics and estimated muscle activations.<br><b>forces_[trial]_.mot</b>: calculated muscle and actuator forces.<br><b>kinetics_[trial]_.mot</b>: generalized joint moments and forces.<br><b>GRF_[trial]_.mot</b>: forces generated by the individual foot–ground contact elements.<br><b>GRF_resultant_[trial]_.mot</b>: resultant ground-reaction forces, centres of pressure, and torques for the left and right sides.</li><li>JointReaction/[trial]/: joint-reaction forces and moments calculated with OpenSim JointReaction Analysis:<br><b>results_JRAforMCF_...sto</b>: reactions acting on the child bodies and expressed in their local frames.<br><b>results_JRAforMCF_parent_...sto</b>: reactions acting on the parent bodies and expressed in their local frames.<br><i>Both variants are provided because the femur is the child body at the hip joint but the parent body at the knee and patellofemoral joints.</i></li><li>ForceDirections/[trial]/femur_l and femur_r: muscle attachment points and lines of action relative to the left and right femur:<br><b>*_vectors.sto</b>: direction vectors of the individual muscle-path segments.<br><b>*_attachments.sto</b>: corresponding attachment or via points.<br><b>*_effective_vectors.sto and *_effective_attachments.sto</b>: effective force directions and application points after combining path segments acting on the femur.<br><b>*_MFD_full.mat</b>: complete MATLAB export containing the muscle-force-direction results.</li><li>Accelerations/[trial]/: linear centre-of-mass accelerations and angular accelerations of both femora.