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Data · collection · 2015

Two new triterpenoids from Nauclea officinalis

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Two new triterpenoids and three 27-nor-triterpenoids were isolated from the stems (with bark) of Nauclea officinalis .

Description

Their structures were identified to be 2β,3β,19α,23-tetrahydroxy-urs-12-en-28-oic acid ( 1 ), 2β,3β,19α,23-tetrahydroxy-urs-12-en-28- O -[β-d-glucopyranosyl (1-2)-β-d-glucopyranosyl] ester ( 2 ), pyrocincholic acid 3β- O -α-l-rhamnopyranoside ( 3 ), pyrocincholic acid 3β- O -α-l-rhamnopyranosy1-28- O -β-d-glucopyranosyl ester ( 4 ), pyrocincholic acid 3β- O -α-l-rhamnopyranosy1-28- O -β-d-glucopyranosyl-(1-6)-β-d-glucopyranosyl ester ( 5 ) by spectroscopic methods including 1D, 2D NMR and HR-MS analyses.

The cytotoxic activity of 1 – 5 against lung cancer A-549 cells was also investigated.

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Cancer 75%
Provenance · 2 source records, 20 field assertions
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DataCite10.6084/m9.figshare.c.202475314 d agoJSON v1
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