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Data · dataset · 2026

<p>Contribution of cDCs and pDCs to type I IFN production and anti-viral CD4(+) T cell responses stimulated with OLL1073R-1.</p>

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<p>(A) Isolated cDCs and pDCs are cultured with or without <i>L</i>. <i>bulgaricus</i> OLL1073R-1 for 24 h.

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IL-12p40, IFN-α2a, IFN-β levels in supernatants were analyzed (n = 3). (B) PBMCs (n = 4), cDCs-depleted PBMCs (n = 3) and pDCs-depleted PBMCs (n = 3) were cultured with or without <i>L</i>. <i>bulgaricus</i> OLL1073R-1 for 24 h.

IFN-α2a, IFN-β levels in supernatants were analyzed. (C) PBMCs, cDCs-depleted PBMCs and pDCs-depleted PBMCs were cultured with or without <i>L</i>. <i>bulgaricus</i> OLL1073R-1 under the stimulation of influenza antigen. The ratio of IFN-γ expressing cells in CD4(+) T<sub>EM</sub> were analyzed 24 h after incubation (n = 5, *: <i>p</i> < 0.05, NS: not significant by Student’s t-test).

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IL-12 levels in supernatants were analyzed 20 h after incubation (n = 3). *: <i>p</i> < 0.05, NS: not significant by Mann-Whitney U test unless otherwise noted. Data below detection limit were calculated as zero.</p>

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ZivaHuboai:figshare.com:article/3402578713 d agoJSON v1
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