<p>Characteristics of participants (n = 81).</p>

However, prevalence of undernutrition in this population is unknown. Therefore, the aim of this study was to determine the nutritional intake and prevalence of undernutrition post-LLA, and to identify determinants of undernutrition.</p> <p>Methods</p><p>In this prospective longitudinal observational study, adults who underwent a dysvascular major LLA were included in six hospitals (n = 81).

At several measurement occasions following amputation (<12 days, 5 weeks, 6 months, 9 months), participants’ nutritional intake (24-hour recall) and nutritional status (Patient-Generated Subjective Global Assessment, body mass index, grip strength, mid upper arm circumference, and triceps skinfold) were determined. Furthermore, the Dutch Healthy Diet index was determined. Potential determinants of undernutrition, i.e., age, sex, Charlson comorbidity index, LLA level, uni/bilateral LLA, education level, living situation, smoking status, pain level, and physical activity level, were assessed using mixed effect models.</p> <p>Results</p><p>Median [Q1; Q3] energy intake was 1647 [1178; 2199], 2053 [1516; 2340], 1920 [1263; 2240], and 1797 [1343; 2211] kcal/day (p = 0.002), and protein intake was 76 [59; 100], 88 [68; 114], 84 [64; 101], and 75 [57; 97] grams/day (p = 0.017) at <12 days, 5 weeks, 6 months, and 9 months post-LLA, respectively.