Data Set accompanying "3D-printed polymer hollow microneedles on microfluidic platforms for minimally invasive interstitial fluid extraction"

Hollow microneedle devices are a promising solution to extract ISF on demand for ex vivo analyses by penetrating the skin with minimal pain. However, traditional microneedles are fabricated, for instance, by etching, which relies on inserting bio-incompatible materials (e.g., silicon) into individuals.

This limits their application time and usually restricts the use of such microneedles to single-time-point measurements. This has motivated the exploration of novel fabrication routes capable of realizing the fine geometries of hollow microneedles with materials that provide sufficient mechanical strength to penetrate the skin. Advances in additive manufacturing now enables the design of polymer-based millimeter-sized structures with micrometer precision by two-photon polymerization (TPP).