Data · collection · 2015
Cytotoxic 19-oxygenated steroids from the South China Sea gorgonian, Pacifigorgia senta
Listed in DataCite
Bioassay guided chemical investigation of the gorgonian Pacifigorgia senta led to the discovery of a new 19-oxygenated steroid, cholesta-5,24-diene-3 β ,7 β ,19-triol ( 1 ), as well as three known steroids ( 2 – 4 ).
Description
The structure of 1 was determined by extensive spectroscopic analysis, including NMR and MS spectra. All of the compounds exhibited cytotoxicities against HepG2, Hep3B, MCF-7/ADR, PC-3 and HCT-116 cell lines, with the IC 50 values ranging from 7.0 to 29.7 μM. It is the first report on the chemical constituents of the coral species P. senta .
Links
Where it is published
- Repository landing page tandf.figshare.com/collections/Cytotoxic_19_oxygenated_steroids_from_the_South_Ch… ↗
landing page · from DataCite
- Repository landing page tandf.figshare.com/collections/Cytotoxic_19_oxygenated_steroids_from_the_South_Ch… ↗
landing page · from DataCite
- DOI doi.org/10.6084/m9.figshare.c.2096567 ↗
DOI / persistent id · from DataCite
- DOI doi.org/10.6084/m9.figshare.c.2096567.v1 ↗
DOI / persistent id · from DataCite
Documentation and papers
Catalogue records · 4
- DataCite API api.datacite.org/dois/10.6084/m9.figshare.c.2096567.v1 ↗
metadata API · from DataCite
- DataCite API api.datacite.org/dois/10.6084/m9.figshare.c.2096567 ↗
metadata API · from DataCite
- DataCite Commons commons.datacite.org/doi.org/10.6084/m9.figshare.c.2096567.v1 ↗
catalogue entry · from DataCite
- DataCite Commons commons.datacite.org/doi.org/10.6084/m9.figshare.c.2096567 ↗
catalogue entry · from DataCite
Topics
- Stated by source
- Biological sciences · Biological sciences · Chemical sciences · Chemical sciences · Sociology · Sociology
- From keywords
- Cancer · Cancer · Ecology · Inorganic chemistry · Social Science · Social Science · Sociology
Provenance · 2 source records, 17 field assertions
| Source | Key | Last seen | Raw |
|---|---|---|---|
| DataCite | 10.6084/m9.figshare.c.2096567 | 14 d ago | JSON v1 |
| DataCite | 10.6084/m9.figshare.c.2096567.v1 | 14 d ago | JSON v1 |
| Field | Assertion | Extractor | Evidence |
|---|---|---|---|
| access_level | source · DataCite | connector:datacite@1.0.0 | /data/attributes/rightsList |
| concepts[disease].local:disease:cancer | mapping · DataCite | vocabulary-mapper@1.0.0 | keywords['Cancer'] |
| concepts[disease].local:disease:cancer | mapping · DataCite | vocabulary-mapper@1.0.0 | keywords['Cancer'] |
| concepts[field].fos:biological-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:biological-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:chemical-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:chemical-sciences | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:sociology | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].fos:sociology | source · DataCite | connector:datacite@1.0.0 | |
| concepts[field].local:field:social-science | mapping · DataCite | vocabulary-mapper@1.0.0 | keywords['Sociology'] |
| concepts[field].local:field:social-science | mapping · DataCite | vocabulary-mapper@1.0.0 | keywords['Sociology'] |
| created_date | source · DataCite | connector:datacite@1.0.0 | |
| description | source · DataCite | connector:datacite@1.0.0 | /data/attributes/descriptions |
| license | source · DataCite | connector:datacite@1.0.0 | /data/attributes/rightsList |
| publication_date | source · DataCite | connector:datacite@1.0.0 | /data/attributes/dates |
| title | source · DataCite | connector:datacite@1.0.0 | /data/attributes/titles/0/title |
| updated_date | source · DataCite | connector:datacite@1.0.0 |